April 9, 2026

Muscles, Bones & Weight Management

Muscles, Bones & Weight Management
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GLP-1 Weight Loss, Muscle Loss & Bone Health in Menopause: What Women Need to Know

Dr. Duncan Turner and nurse practitioner Sophie Mengele discuss the impact of GLP-1 weight loss medications on muscle mass and bone health, especially for women undergoing hormonal changes and menopause. They note that while weight management and exercise are proven to support longevity, weight loss commonly leads to reduced muscle strength, and diminished appetite on medication may worsen inadequate protein intake and low activity. They emphasize that muscle mass and physical strength are associated with longevity, while visceral fat is tied to metabolic disease, and thinning can be particularly risky for osteoporosis. The episode highlights monitoring tools such as DEXA scans, bone scores, and body composition assessments, plus the importance of strength training, supplements, and considering hormones such as estrogen and possibly testosterone under medical oversight.

00:00 Podcast Welcome

00:24 Today’s Topic Overview

00:45 GLP One Risks

01:09 Protein and Diet Reality

02:09 Muscle Loss Matters

02:33 Longevity Metrics

02:49 Testing and Hormones

03:47 Osteoporosis in Midlife

04:26 Monitoring and Safety

04:44 Wrap Up Thanks

Episode Resources

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